2elx

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Solution structure of the 8th C2H2 zinc finger of mouse Zinc finger protein 406Solution structure of the 8th C2H2 zinc finger of mouse Zinc finger protein 406

Structural highlights

2elx is a 1 chain structure with sequence from Mus musculus. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:Solution NMR
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT, TOPSAN

Function

ZFAT_MOUSE May be involved in transcriptional regulation. Overexpression causes down-regulation of a number of genes involved in the immune response. Some genes are also up-regulated.[1]

References

  1. ↑ Koyanagi M, Nakabayashi K, Fujimoto T, Gu N, Baba I, Takashima Y, Doi K, Harada H, Kato N, Sasazuki T, Shirasawa S. ZFAT expression in B and T lymphocytes and identification of ZFAT-regulated genes. Genomics. 2008 May;91(5):451-7. Epub 2008 Mar 7. PMID:18329245 doi:http://dx.doi.org/S0888-7543(08)00039-6
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OCA
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