2d2w

Solution structure and Dynamics of the DNA-Binding Domain of Myocyte Nuclear FactorSolution structure and Dynamics of the DNA-Binding Domain of Myocyte Nuclear Factor

Structural highlights

2d2w is a 1 chain structure with sequence from Mus musculus. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:	Solution NMR
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

FOXK1_MOUSE Transcriptional regulator that binds to the upstream enhancer region (CCAC box) of myoglobin gene. Has a role in myogenic differentiation and in remodeling processes of adult muscles that occur in response to physiological stimuli.^[1] ^[2]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

References

↑ Bassel-Duby R, Hernandez MD, Yang Q, Rochelle JM, Seldin MF, Williams RS. Myocyte nuclear factor, a novel winged-helix transcription factor under both developmental and neural regulation in striated myocytes. Mol Cell Biol. 1994 Jul;14(7):4596-605. PMID:8007964
↑ Yang Q, Bassel-Duby R, Williams RS. Transient expression of a winged-helix protein, MNF-beta, during myogenesis. Mol Cell Biol. 1997 Sep;17(9):5236-43. PMID:9271401

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OCA

[1] Bassel-Duby R, Hernandez MD, Yang Q, Rochelle JM, Seldin MF, Williams RS. Myocyte nuclear factor, a novel winged-helix transcription factor under both developmental and neural regulation in striated myocytes. Mol Cell Biol. 1994 Jul;14(7):4596-605. PMID:8007964

[2] Yang Q, Bassel-Duby R, Williams RS. Transient expression of a winged-helix protein, MNF-beta, during myogenesis. Mol Cell Biol. 1997 Sep;17(9):5236-43. PMID:9271401

[1]

[2]

2d2w

Solution structure and Dynamics of the DNA-Binding Domain of Myocyte Nuclear FactorSolution structure and Dynamics of the DNA-Binding Domain of Myocyte Nuclear Factor

Structural highlights

Function

Evolutionary Conservation

See Also

References

Contents

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2d2w

Solution structure and Dynamics of the DNA-Binding Domain of Myocyte Nuclear FactorSolution structure and Dynamics of the DNA-Binding Domain of Myocyte Nuclear Factor

Structural highlights

Function

Evolutionary Conservation

See Also

References

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