2d2p

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The solution structure of micelle-bound peptideThe solution structure of micelle-bound peptide

Structural highlights

2d2p is a 1 chain structure with sequence from Homo sapiens. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:Solution NMR, 20 models
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

PACA_HUMAN Binding to its receptor activates G proteins and stimulates adenylate cyclase in pituitary cells.[1]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

References

  1. Inooka H, Ohtaki T, Kitahara O, Ikegami T, Endo S, Kitada C, Ogi K, Onda H, Fujino M, Shirakawa M. Conformation of a peptide ligand bound to its G-protein coupled receptor. Nat Struct Biol. 2001 Feb;8(2):161-5. PMID:11175907 doi:http://dx.doi.org/10.1038/84159
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