2cof

Solution structure of the C-terminal PH domain of hypothetical protein KIAA1914 from humanSolution structure of the C-terminal PH domain of hypothetical protein KIAA1914 from human

Structural highlights

2cof is a 1 chain structure with sequence from Homo sapiens. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:	Solution NMR
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT, TOPSAN

Function

AF1L2_HUMAN May play a role in a signaling cascade by enhancing the kinase activity of SRC. Contributes to SRC-regulated transcription activation.^[1]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

References

↑ Xu J, Bai XH, Lodyga M, Han B, Xiao H, Keshavjee S, Hu J, Zhang H, Yang BB, Liu M. XB130, a novel adaptor protein for signal transduction. J Biol Chem. 2007 Jun 1;282(22):16401-12. Epub 2007 Apr 5. PMID:17412687 doi:http://dx.doi.org/10.1074/jbc.M701684200

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OCA

[1] Xu J, Bai XH, Lodyga M, Han B, Xiao H, Keshavjee S, Hu J, Zhang H, Yang BB, Liu M. XB130, a novel adaptor protein for signal transduction. J Biol Chem. 2007 Jun 1;282(22):16401-12. Epub 2007 Apr 5. PMID:17412687 doi:http://dx.doi.org/10.1074/jbc.M701684200

[1]

2cof

Solution structure of the C-terminal PH domain of hypothetical protein KIAA1914 from humanSolution structure of the C-terminal PH domain of hypothetical protein KIAA1914 from human

Structural highlights

Function

Evolutionary Conservation

References

Contents

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2cof

Solution structure of the C-terminal PH domain of hypothetical protein KIAA1914 from humanSolution structure of the C-terminal PH domain of hypothetical protein KIAA1914 from human

Structural highlights

Function

Evolutionary Conservation

References

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Navigation menu

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