2ckc

Solution structures of the BRK domains of the human Chromo Helicase Domain 7 and 8, reveals structural similarity with GYF domain suggesting a role in protein interactionSolution structures of the BRK domains of the human Chromo Helicase Domain 7 and 8, reveals structural similarity with GYF domain suggesting a role in protein interaction

Structural highlights 2ckc is a 1 chain structure with sequence from Homo sapiens. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: Solution NMR Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Disease CHD7_HUMAN CHARGE syndrome;Normosmic congenital hypogonadotropic hypogonadism;Omenn syndrome;Kallmann syndrome. The disease is caused by variants affecting the gene represented in this entry. Disease susceptibility is associated with variants affecting the gene represented in this entry. The disease is caused by variants affecting the gene represented in this entry. Function CHD7_HUMAN Probable transcription regulator. Maybe involved in the in 45S precursor rRNA production. Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. See Also Chromodomain-helicase-DNA-binding protein 3D structures Helicase 3D structures

spinqualitylabelsall models 2ckc Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image