2c2h
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CRYSTAL STRUCTURE OF THE HUMAN RAC3 IN COMPLEX WITH GDPCRYSTAL STRUCTURE OF THE HUMAN RAC3 IN COMPLEX WITH GDP
Structural highlights
FunctionRAC3_HUMAN Plasma membrane-associated small GTPase which cycles between an active GTP-bound and inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses, such as cell spreading and the formation of actin-based protusions including lamellipodia and membrane ruffles.[1] Evolutionary Conservation![]() Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. See AlsoReferences |
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