2bo9

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Human carboxypeptidase A4 in complex with human latexin.Human carboxypeptidase A4 in complex with human latexin.

Structural highlights

2bo9 is a 4 chain structure with sequence from Homo sapiens. This structure supersedes the now removed PDB entry 2bk7. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.6Å
Ligands:, , , ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

CBPA4_HUMAN Metalloprotease that could be involved in the histone hyperacetylation pathway.[1]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

References

  1. Huang H, Reed CP, Zhang JS, Shridhar V, Wang L, Smith DI. Carboxypeptidase A3 (CPA3): a novel gene highly induced by histone deacetylase inhibitors during differentiation of prostate epithelial cancer cells. Cancer Res. 1999 Jun 15;59(12):2981-8. PMID:10383164

2bo9, resolution 1.60Å

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OCA