1zv1
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Crystal structure of the dimerization domain of doublesex protein from D. melanogasterCrystal structure of the dimerization domain of doublesex protein from D. melanogaster
Structural highlights
FunctionDSX_DROME Controls somatic sexual differentiation. Binds directly and specifically to the FBE (fat body enhancer) of the yolk protein 1 and 2 genes (Yp1 and Yp2). This enhancer is sufficient to direct the female-specific transcription characteristic of the Yp genes in adult fat bodies. Involved in regulation of male-specific expression of takeout in brain-associated fat body.[1] Evolutionary Conservation![]() Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. References
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