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Crystal Structure of Guinea Pig 11beta-Hydroxysteroid Dehydrogenase Type 1Crystal Structure of Guinea Pig 11beta-Hydroxysteroid Dehydrogenase Type 1
Structural highlights
FunctionDHI1_CAVPO Catalyzes reversibly the conversion of cortisol to the inactive metabolite cortisone. Catalyzes reversibly the conversion of 7-ketocholesterol to 7-beta-hydroxycholesterol. In intact cells, the reaction runs only in one direction, from 7-ketocholesterol to 7-beta-hydroxycholesterol (By similarity).[1] Evolutionary Conservation![]() Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. See AlsoReferences |
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