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Solution Structure of the N-terminal Ras-binding Domain (RBD) in Human a-Raf KinaseSolution Structure of the N-terminal Ras-binding Domain (RBD) in Human a-Raf Kinase
Structural highlights
FunctionARAF_HUMAN Involved in the transduction of mitogenic signals from the cell membrane to the nucleus.[1] Isoform 2: Serves as a positive regulator of myogenic differentiation by inducing cell cycle arrest, the expression of myogenin and other muscle-specific proteins, and myotube formation.[2] Evolutionary Conservation![]() Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. See AlsoReferences
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