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Solution structure of the PDZ domain of mouse Rhophilin-2Solution structure of the PDZ domain of mouse Rhophilin-2
Structural highlights
FunctionRHPN2_MOUSE Binds specifically to GTP-Rho. May function in a Rho pathway to limit stress fiber formation and/or increase the turnover of F-actin structures in the absence of high levels of RhoA activity (By similarity). Evolutionary Conservation![]() Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. |
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