1u5t
Jump to navigation
Jump to search
Structure of the ESCRT-II endosomal trafficking complexStructure of the ESCRT-II endosomal trafficking complex
Structural highlights
FunctionSNF8_YEAST Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-II complex is probably involved in the recruitment of the ESCRT-III complex. Evolutionary Conservation![]() Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. |
|