1sbt

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ATOMIC COORDINATES FOR SUBTILISIN BPN (OR NOVO)ATOMIC COORDINATES FOR SUBTILISIN BPN (OR NOVO)

Structural highlights

1sbt is a 1 chain structure with sequence from Bacillus amyloliquefaciens. The October 2011 RCSB PDB Molecule of the Month feature on PDB Pioneers by David Goodsell is 10.2210/rcsb_pdb/mom_2011_10. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.5Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

SUBT_BACAM Subtilisin is an extracellular alkaline serine protease, it catalyzes the hydrolysis of proteins and peptide amides. Has a high substrate specificity to fibrin.[1]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

References

  1. ↑ Peng Y, Huang Q, Zhang RH, Zhang YZ. Purification and characterization of a fibrinolytic enzyme produced by Bacillus amyloliquefaciens DC-4 screened from douchi, a traditional Chinese soybean food. Comp Biochem Physiol B Biochem Mol Biol. 2003 Jan;134(1):45-52. PMID:12524032

1sbt, resolution 2.50Å

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OCA
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