1q3l

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Chromodomain Of HP1 Complexed With Histone H3 Tail Containing monomethyllysine 9.Chromodomain Of HP1 Complexed With Histone H3 Tail Containing monomethyllysine 9.

Structural highlights

1q3l is a 2 chain structure with sequence from Drosophila melanogaster and Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.64Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

HP1_DROME Structural component of heterochromatin, involved in gene repression and the modification of position-effect-variegation. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

1q3l, resolution 1.64Å

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OCA