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THE STRUCTURE OF THE HMG BOX AND ITS INTERACTION WITH DNATHE STRUCTURE OF THE HMG BOX AND ITS INTERACTION WITH DNA
Structural highlights
FunctionHMGB1_CRIGR DNA binding proteins that associates with chromatin and has the ability to bend DNA. Binds preferentially single-stranded DNA. Involved in V(D)J recombination by acting as a cofactor of the RAG complex. Acts by stimulating cleavage and RAG protein binding at the 23 bp spacer of conserved recombination signal sequences (RSS). Heparin-binding protein that has a role in the extension of neurite-type cytoplasmic processes in developing cells (By similarity). Evolutionary Conservation![]() Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. See Also |
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