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Crystal structure of the alpha-X beta2 integrin I domainCrystal structure of the alpha-X beta2 integrin I domain
Structural highlights
FunctionITAX_HUMAN Integrin alpha-X/beta-2 is a receptor for fibrinogen. It recognizes the sequence G-P-R in fibrinogen. It mediates cell-cell interaction during inflammatory responses. It is especially important in monocyte adhesion and chemotaxis. Evolutionary Conservation![]() Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. See Also |
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