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70KD HEAT SHOCK COGNATE PROTEIN ATPASE DOMAIN, K71M MUTANT70KD HEAT SHOCK COGNATE PROTEIN ATPASE DOMAIN, K71M MUTANT
Structural highlights
FunctionHSP7C_BOVIN Acts as a repressor of transcriptional activation. Inhibits the transcriptional coactivator activity of CITED1 on Smad-mediated transcription. Chaperone. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. May have a scaffolding role in the spliceosome assembly as it contacts all other components of the core complex (By similarity). Evolutionary Conservation![]() Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. See Also |
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