1jpu

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Crystal Structure of Bacillus Stearothermophilus Glycerol DehydrogenaseCrystal Structure of Bacillus Stearothermophilus Glycerol Dehydrogenase

Structural highlights

1jpu is a 1 chain structure with sequence from Geobacillus stearothermophilus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.8Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

GLDA_GEOSE Catalyzes the NAD-dependent oxidation of glycerol to dihydroxyacetone (glycerone). Allows microorganisms to utilize glycerol as a source of carbon under anaerobic conditions. Is also able to use various diols as substrates, such as propan-1,2-diol, butan-2,3-diol, ethan-1,2-diol, and 3-mercapto-1,2-dihydroxypropane.[1]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

References

  1. Spencer P, Bown KJ, Scawen MD, Atkinson T, Gore MG. Isolation and characterisation of the glycerol dehydrogenase from Bacillus stearothermophilus. Biochim Biophys Acta. 1989 Feb 23;994(3):270-9. PMID:2493267

1jpu, resolution 1.80Å

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OCA