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Crystal structure of transcriptional regulator (TM1602) from Thermotoga maritima at 2.3 A resolutionCrystal structure of transcriptional regulator (TM1602) from Thermotoga maritima at 2.3 A resolution
Structural highlights
FunctionNIAR_THEMA Probably functions to regulate transcription of NAD metabolic genes. Binds to DNA upstream of the probable nadBII/nadA/nadC and niaRP operons in a nicotinic acid dependent fashion. Nicotinic acid may be a corepressor. Evolutionary Conservation![]() Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. |
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