1ems

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CRYSTAL STRUCTURE OF THE C. ELEGANS NITFHIT PROTEINCRYSTAL STRUCTURE OF THE C. ELEGANS NITFHIT PROTEIN

Structural highlights

1ems is a 2 chain structure with sequence from Caenorhabditis elegans. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.8Å
Ligands:, ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

NFT1_CAEEL Cleaves A-5'-PPP-5'A to yield AMP and ADP.[1]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

References

  1. Pace HC, Hodawadekar SC, Draganescu A, Huang J, Bieganowski P, Pekarsky Y, Croce CM, Brenner C. Crystal structure of the worm NitFhit Rosetta Stone protein reveals a Nit tetramer binding two Fhit dimers. Curr Biol. 2000 Jul 27-Aug 10;10(15):907-17. PMID:10959838

1ems, resolution 2.80Å

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OCA