1ds7
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A MINOR FMN-DEPENDENT NITROREDUCTASE FROM ESCHERICHIA COLI BA MINOR FMN-DEPENDENT NITROREDUCTASE FROM ESCHERICHIA COLI B
Structural highlights
FunctionNFSB_ECOLI Reduction of a variety of nitroaromatic compounds using NADH (and to lesser extent NADPH) as source of reducing equivalents; two electrons are transferred. Capable of reducing nitrofurazone, quinones and the anti-tumor agent CB1954 (5-(aziridin-1-yl)-2,4-dinitrobenzamide). The reduction of CB1954 results in the generation of cytotoxic species.[1] Evolutionary Conservation![]() Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. See AlsoReferences
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