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CRYSTAL STRUCTURE OF HUMAN PROFILIN IICRYSTAL STRUCTURE OF HUMAN PROFILIN II
Structural highlights
FunctionPROF2_HUMAN Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG. Evolutionary Conservation![]() Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. See Also |
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