1a59

COLD-ACTIVE CITRATE SYNTHASECOLD-ACTIVE CITRATE SYNTHASE

Structural highlights 1a59 is a 1 chain structure with sequence from Antarctic bacterium DS2-3R. The September 2007 RCSB PDB Molecule of the Month feature on Citrate Synthase by David S. Goodsell is 10.2210/rcsb_pdb/mom_2007_9. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 2.09Å Ligands: , Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function PRPC_ABDS2 Involved in the catabolism of short chain fatty acids (SCFA) via the tricarboxylic acid (TCA)(acetyl degradation route) and via the 2-methylcitrate cycle I (propionate degradation route). Catalyzes the Claisen condensation of propionyl-CoA and oxaloacetate (OAA) to yield 2-methylcitrate (2-MC) and CoA. Also catalyzes the condensation of oxaloacetate with acetyl-CoA but with a lower specificity. Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. See Also Citrate Synthase 3D structures

spinqualitylabelsall models 1a59, resolution 2.09Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image