3gpt
Crystal structure of the yeast 20S proteasome in complex with Salinosporamide derivatives: slow substrate ligandCrystal structure of the yeast 20S proteasome in complex with Salinosporamide derivatives: slow substrate ligand
Template:ABSTRACT PUBMED 19678642
About this StructureAbout this Structure
3GPT is a 28 chains structure of sequences from Saccharomyces cerevisiae. Full crystallographic information is available from OCA.
ReferenceReference
- ↑ Groll M, McArthur KA, Macherla VR, Manam RR, Potts BC. Snapshots of the fluorosalinosporamide/20S complex offer mechanistic insights for fine tuning proteasome inhibition. J Med Chem. 2009 Sep 10;52(17):5420-8. PMID:19678642 doi:10.1021/jm900559x
Page seeded by OCA on Wed Sep 16 09:01:45 2009
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OCACategories:
- Pages with broken file links
- Proteasome endopeptidase complex
- Saccharomyces cerevisiae
- Arthur, K A.M.
- Groll, M.
- Macherla, V R.
- Manam, R R.
- Potts, C B.
- Cancer therapy
- Cytoplasm
- Hydrolase
- Immunology
- Inhibitor
- Isopeptide bond
- Nucleus
- Phosphoprotein
- Protease
- Proteasome
- Threonine protease
- Time dependent leaving group elimination
- Ubiquitin
- Ubl conjugation
- Zymogen