3ii6
Structure of human Xrcc4 in complex with the tandem BRCT domains of DNA LigaseIV.Structure of human Xrcc4 in complex with the tandem BRCT domains of DNA LigaseIV.
DiseaseDisease
Known disease associated with this structure: LIG4 syndrome OMIM:[601837], Multiple myeloma, resistance to OMIM:[601837]
About this StructureAbout this Structure
3II6 is a 6 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.
ReferenceReference
- ↑ Wu PY, Frit P, Meesala S, Dauvillier S, Modesti M, Andres SN, Huang Y, Sekiguchi J, Calsou P, Salles B, Junop MS. Structural and functional interaction between the human DNA repair proteins DNA ligase IV and XRCC4. Mol Cell Biol. 2009 Jun;29(11):3163-72. Epub 2009 Mar 30. PMID:19332554 doi:10.1128/MCB.01895-08
Page seeded by OCA on Wed Aug 12 12:43:59 2009
Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)
OCACategories:
- Pages with broken file links
- Homo sapiens
- Junop, M.
- Meesala, S.
- Alternative splicing
- Atp-binding
- Brct
- Cell cycle
- Cell division
- Coiled coil
- Disease mutation
- Dna damage
- Dna ligase iv
- Dna recombination
- Dna repair
- Dna replication
- Isopeptide bond
- Ligase
- Ligase/dna binding protein complex
- Magnesium
- Metal-binding
- Nhej
- Nucleotide-binding
- Nucleus
- Phosphoprotein
- Polymorphism
- Scid
- Ubl conjugation
- Xrcc4