190d
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CRYSTAL STRUCTURE OF A FOUR-STRANDED INTERCALATED DNA: D(C4)
OverviewOverview
The crystal structure of d(C4) solved at 2.3-A resolution reveals a, four-stranded molecule composed of two interdigitated or intercalated, duplexes. The duplexes are held together by hemiprotonated, cytosine-cytosine base pairs and are parallel stranded, but the two, duplexes point in opposite directions. The molecule has a slow, right-handed twist of 12.4 degrees between covalently linked cytosine base, pairs, and the base stacking distance is 3.1 A. This is in general, agreement with the NMR studies. A biological role for DNA in this, conformation is suggested.
About this StructureAbout this Structure
190D is a Protein complex structure of sequences from [1]. Full crystallographic information is available from OCA.
ReferenceReference
Crystal structure of a four-stranded intercalated DNA: d(C4)., Chen L, Cai L, Zhang X, Rich A, Biochemistry. 1994 Nov 22;33(46):13540-6. PMID:7947764
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