Sandbox1234
This sandbox is in use until June 1, 2009 for UMass Chemistry 490a. Others please do not edit this page. Thanks!
GlucokinaseGlucokinase
The shown representation is a DNA:RAN hybrid duplex. This is the in orange and this is the in green. We can choose to see the base pairs, which show very neatly. First, the G-C pairs: are in blue and dC-G are in yellow.
Structure
| |||||||||
| 1v4s, resolution 2.30Å () | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Ligands: | , , | ||||||||
| Activity: | Hexokinase, with EC number 2.7.1.1 | ||||||||
| Related: | 1v4t | ||||||||
| |||||||||
| |||||||||
| Resources: | FirstGlance, OCA, RCSB, PDBsum | ||||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||||
The glucokinase has 18 (unless we counted wrong), 13 (this one is for sure), and 3 : a , amide or MRK in short, and last a sugar (alpha-d-glucose) or simply GLC.
Purple denotes all the sections of the protein: the hydrophillic areas that dominate the outer surface which comes in contact with aqueous environments. In this view we can see very neatly how the beta sheets alternate in polarity in a 'zigzag manner, and how the alpha helices are roughly 2-3 polar (while the inner protein is obviously hydrophobic). The , in particular, shows how the surface is dominantly hydrophillic.
ReferenceReference
http://www.proteopedia.org/wiki/index.php/1v4s http://en.wikipedia.org/wiki/Glucokinase
--Tinuke (Abike etc. etc. etc.) Adeyemi and Niva Ran