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Crystal Structure of Human Drug Metabolizing Cytochrome P450 2C8Crystal Structure of Human Drug Metabolizing Cytochrome P450 2C8

By Amit Shavit

3cin, resolution 1.70Å ()

Ligands:

, ,

Gene:

TM1419, TM_1419 (Thermotoga maritima MSB8)

Activity:

Inositol-3-phosphate synthase, with EC number 5.5.1.4

Structural annotation:
Resources:	CATH : 3Cina01, 3Cina02 InterPro : Ipr016040, Ipr013021, Ipr002587 Pfam : PF07994

Evolutionary conservation:

Toggle Conservation Colors:	Rows = identical sequences:
Further Information:	Caveats, Explanation, Complete Results at ConSurfDB

Resources:

FirstGlance, OCA, RCSB, PDBsum, TOPSAN

Coordinates:

save as pdb, mmCIF, xml

ProteinProtein

are shown in brown

StructureStructure

are portrayed in purple.

are portrayed in blue

in red

in dark green

are shown in brown

ReferenceReference

Schoch GA, Yano JK, Wester MR, Griffin KJ, Stout CD, Johnson EF Structure of human microsomal cytochrome P450 2C8. Evidence for a peripheral fatty acid binding site. J Biol Chem. 2004 Mar 5;279(10):9497-503. Epub 2003 Dec 15. PMID:14676196

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Amit Shavit