Sandbox 72

Please do NOT make changes to this Sandbox until after April 30, 2009. Sandboxes 60-80 are reserved until then for use by students of East High, Buffalo NY. FIBRINFIBRIN This protein works in the blood to quickly blocks any damage to the circulatory system, creating a temporary patch that allows time for more permanent repairs. It is a strong protein that is inactive until activated when a cut or lacerition to the skin is present. FUNCTIONFUNCTION Fibrin in the blood works along with two other molecules. These molecules are platelets (small fragments of blood cells that circulate in the blood), and neighboring blood vessels which constrict when needed. These methods work together along with Fibrin to create scabs which stop the flow of blood. spinqualitylabelsall models PDB ID 1m1j Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image 1m1j, resolution 2.70Å () Ligands: , , Related: 1ei3, 1fzc Structural annotation: Resources: CATH : 1M1Ja00, 1M1Jb02, 1M1Jb01, 1M1Jb03, 1M1Jc01, 1M1Jc02, 1M1Jc03, 1M1Jd00, 1M1Je01, 1M1Je03, 1M1Je02, 1M1Jf01, 1M1Jf02, 1M1Jf03 InterPro : Ipr012290, Ipr014716, Ipr014814, Ipr002181, Ipr014715 Pfam : PF08702, PF00147 SCOP : d1m1ja_, d1m1jf1, d1m1jf2 UniProt : P14448, Q02020, O93568 Functional annotation: Cellular component: fibrinogen complex Biological process: signal transduction blood coagulation platelet activation protein polymerization Molecular function: protein binding, bridging receptor binding Evolutionary conservation: Toggle Conservation Colors: Rows = identical sequences: Further Information: Caveats, Explanation, Complete Results at ConSurfDB Resources: FirstGlance, OCA, PDBsum, RCSB Coordinates: save as pdb, mmCIF, xml