3f9n

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Template:STRUCTURE 3f9n

File:3f9n.png

Crystal structure of chk1 kinase in complex with inhibitor 38Crystal structure of chk1 kinase in complex with inhibitor 38

Template:ABSTRACT PUBMED 19155174

About this StructureAbout this Structure

3F9N is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

ReferenceReference

^{[xtra 1]}

↑ Converso A, Hartingh T, Garbaccio RM, Tasber E, Rickert K, Fraley ME, Yan Y, Kreatsoulas C, Stirdivant S, Drakas B, Walsh ES, Hamilton K, Buser CA, Mao X, Abrams MT, Beck SC, Tao W, Lobell R, Sepp-Lorenzino L, Zugay-Murphy J, Sardana V, Munshi SK, Jezequel-Sur SM, Zuck PD, Hartman GD. Development of thioquinazolinones, allosteric Chk1 kinase inhibitors. Bioorg Med Chem Lett. 2009 Feb 15;19(4):1240-4. Epub 2008 Dec 24. PMID:19155174 doi:10.1016/j.bmcl.2008.12.076

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OCA

[1] Converso A, Hartingh T, Garbaccio RM, Tasber E, Rickert K, Fraley ME, Yan Y, Kreatsoulas C, Stirdivant S, Drakas B, Walsh ES, Hamilton K, Buser CA, Mao X, Abrams MT, Beck SC, Tao W, Lobell R, Sepp-Lorenzino L, Zugay-Murphy J, Sardana V, Munshi SK, Jezequel-Sur SM, Zuck PD, Hartman GD. Development of thioquinazolinones, allosteric Chk1 kinase inhibitors. Bioorg Med Chem Lett. 2009 Feb 15;19(4):1240-4. Epub 2008 Dec 24. PMID:19155174 doi:10.1016/j.bmcl.2008.12.076

[xtra 1]