Rebecca Martin/Sandbox1

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IgAIgA

Template:STRUCTURE 3cm9


IntroductionIntroduction

Dimeric and Secretory IgADimeric and Secretory IgA

Secretory Component and Polyimmunoglobulin receptorSecretory Component and Polyimmunoglobulin receptor

Insights into FunctionInsights into Function

EvolutionEvolution

Implications in Science and MedicineImplications in Science and Medicine

Limitations of the Current StudiesLimitations of the Current Studies

Questions for the FutureQuestions for the Future

This is the secretory component.

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LinksLinks

IgA Model of human IgA2 determined by solution scattering, curve fitting and homology modelling 1r70

Crystal structure of human FcaRI bound to IgA1-Fc 1ow0

Solution structure of human dimeric immunoglobulin A 2qtj

Solution structure of human secretory IgA1 3chn

Solution Structure of Human SIgA2 3cm9

Solution structure of human secretory component 2ocw


Receptors

Crystal Structure of a Ligand-Binding Domain of the Human Polymeric Ig Receptor, pIgR 1XED

Crystal structure of human FcaRI 10vz

Crystal structure of a Staphylococcus aureus protein (SSL7) in complex with Fc of human IgA1 2qej


For Comparison

IgM: Solution structure of human Immunoglobulin M 2rcj IgG: IgD: IgE:


ReferencesReferences

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Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Rebecca Martin, Jaime Prilusky