3e88
Crystal structures of the kinase domain of AKT2 in complex with ATP-competitive inhibitorsCrystal structures of the kinase domain of AKT2 in complex with ATP-competitive inhibitors
Template:ABSTRACT PUBMED 19179070
DiseaseDisease
Known disease associated with this structure: Diabetes mellitus, type II OMIM:[164731]
About this StructureAbout this Structure
3E88 is a 4 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.
ReferenceReference
- ↑ Rouse MB, Seefeld MA, Leber JD, McNulty KC, Sun L, Miller WH, Zhang S, Minthorn EA, Concha NO, Choudhry AE, Schaber MD, Heerding DA. Aminofurazans as potent inhibitors of AKT kinase. Bioorg Med Chem Lett. 2009 Mar 1;19(5):1508-11. Epub 2009 Jan 9. PMID:19179070 doi:10.1016/j.bmcl.2009.01.002
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