1o42

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Template:STRUCTURE 1o42

File:1o42.png

CRYSTAL STRUCTURE OF SH2 IN COMPLEX WITH RU81843.CRYSTAL STRUCTURE OF SH2 IN COMPLEX WITH RU81843.

Template:ABSTRACT PUBMED 14613321

DiseaseDisease

Known disease associated with this structure: Colon cancer, advanced OMIM:[190090]

About this StructureAbout this Structure

1O42 is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

ReferenceReference

^{[xtra 1]}

↑ Lange G, Lesuisse D, Deprez P, Schoot B, Loenze P, Benard D, Marquette JP, Broto P, Sarubbi E, Mandine E. Requirements for specific binding of low affinity inhibitor fragments to the SH2 domain of (pp60)Src are identical to those for high affinity binding of full length inhibitors. J Med Chem. 2003 Nov 20;46(24):5184-95. PMID:14613321 doi:http://dx.doi.org/10.1021/jm020970s

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OCA

[1] Lange G, Lesuisse D, Deprez P, Schoot B, Loenze P, Benard D, Marquette JP, Broto P, Sarubbi E, Mandine E. Requirements for specific binding of low affinity inhibitor fragments to the SH2 domain of (pp60)Src are identical to those for high affinity binding of full length inhibitors. J Med Chem. 2003 Nov 20;46(24):5184-95. PMID:14613321 doi:http://dx.doi.org/10.1021/jm020970s

[xtra 1]