1rd3

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Template:STRUCTURE 1rd3

File:1rd3.png

2.5A Structure of Anticoagulant Thrombin Variant E217K2.5A Structure of Anticoagulant Thrombin Variant E217K

Template:ABSTRACT PUBMED 15075325

DiseaseDisease

Known disease associated with this structure: Dysprothrombinemia OMIM:[176930], Hyperprothrombinemia OMIM:[176930], Hypoprothrombinemia OMIM:[176930]

About this StructureAbout this Structure

1RD3 is a 4 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

ReferenceReference

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↑ Carter WJ, Myles T, Gibbs CS, Leung LL, Huntington JA. Crystal structure of anticoagulant thrombin variant E217K provides insights into thrombin allostery. J Biol Chem. 2004 Jun 18;279(25):26387-94. Epub 2004 Apr 9. PMID:15075325 doi:http://dx.doi.org/10.1074/jbc.M402364200

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OCA

[1] Carter WJ, Myles T, Gibbs CS, Leung LL, Huntington JA. Crystal structure of anticoagulant thrombin variant E217K provides insights into thrombin allostery. J Biol Chem. 2004 Jun 18;279(25):26387-94. Epub 2004 Apr 9. PMID:15075325 doi:http://dx.doi.org/10.1074/jbc.M402364200

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