Template:STRUCTURE 2hg8

File:2hg8.png

Crystal Structure of Cys315Ala mutant of human mitochondrial branched chain aminotransferase complexed with its substrate mimic, N-methyl leucine.Crystal Structure of Cys315Ala mutant of human mitochondrial branched chain aminotransferase complexed with its substrate mimic, N-methyl leucine.

Template:ABSTRACT PUBMED 17050531

About this StructureAbout this Structure

2HG8 is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

ReferenceReference

[xtra 1][xtra 2][xtra 3]

  1. Yennawar NH, Islam MM, Conway M, Wallin R, Hutson SM. Human mitochondrial branched chain aminotransferase isozyme: structural role of the CXXC center in catalysis. J Biol Chem. 2006 Dec 22;281(51):39660-71. Epub 2006 Oct 18. PMID:17050531 doi:10.1074/jbc.M607552200
  2. Davoodi J, Drown PM, Bledsoe RK, Wallin R, Reinhart GD, Hutson SM. Overexpression and characterization of the human mitochondrial and cytosolic branched-chain aminotransferases. J Biol Chem. 1998 Feb 27;273(9):4982-9. PMID:9478945
  3. Bledsoe RK, Dawson PA, Hutson SM. Cloning of the rat and human mitochondrial branched chain aminotransferases (BCATm). Biochim Biophys Acta. 1997 Apr 25;1339(1):9-13. PMID:9165094

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