2fz2
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Structure of Turnip Yellow Mosaic Virus at 100 K
OverviewOverview
Difference electron density maps, based on structure factor amplitudes and, experimental phases from crystals of wild-type turnip yellow mosaic virus, and those of empty capsids prepared by freeze-thawing, show a large, portion of the encapsidated RNA to have an icosahedral distribution. Four, unique segments of base-paired, double-helical RNA, one to two turns in, length, lie between 33-A and 101-A radius and are organized about either, 2-fold or 5-fold icosahedral axes. In addition, single-stranded loops of, RNA invade the pentameric and hexameric capsomeres where they contact the, interior capsid surface. The remaining RNA, not seen in electron density, maps, must serve as connecting links between these secondary structural, elements and is likely icosahedrally disordered. The distribution of RNA, observed crystallographically appears to be in agreement with models based, on biochemical data and secondary structural analyses.
About this StructureAbout this Structure
2FZ2 is a Single protein structure of sequence from Turnip yellow mosaic virus (isolate australia). Full crystallographic information is available from OCA.
ReferenceReference
The RNA of turnip yellow mosaic virus exhibits icosahedral order., Larson SB, Lucas RW, Greenwood A, McPherson A, Virology. 2005 Apr 10;334(2):245-54. PMID:15780874
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