2fk6
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Crystal Structure of RNAse Z/tRNA(Thr) complex
OverviewOverview
The highly conserved ribonuclease RNase Z catalyzes the endonucleolytic, removal of the 3' extension of the majority of tRNA precursors. Here we, present the structure of the complex between Bacillus subtilis RNase Z and, tRNA(Thr), the first structure of a ribonucleolytic processing enzyme, bound to tRNA. Binding of tRNA to RNase Z causes conformational changes in, both partners to promote reorganization of the catalytic site and tRNA, cleavage.
About this StructureAbout this Structure
2FK6 is a Protein complex structure of sequences from Bacillus subtilis with ZN, MES and GOL as ligands. Active as Ribonuclease Z, with EC number 3.1.26.11 Full crystallographic information is available from OCA.
ReferenceReference
Structure of the ubiquitous 3' processing enzyme RNase Z bound to transfer RNA., Li de la Sierra-Gallay I, Mathy N, Pellegrini O, Condon C, Nat Struct Mol Biol. 2006 Apr;13(4):376-7. Epub 2006 Mar 5. PMID:16518398
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