2auh

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File:2auh.png

Template:STRUCTURE 2auh

Crystal structure of the Grb14 BPS region in complex with the insulin receptor tyrosine kinaseCrystal structure of the Grb14 BPS region in complex with the insulin receptor tyrosine kinase

Template:ABSTRACT PUBMED 16246733

DiseaseDisease

Known disease associated with this structure: Diabetes mellitus, insulin-resistant, with acanthosis nigricans OMIM:[147670], Hyperinsulinemic hypoglycemia, familial, 5 OMIM:[147670], Leprechaunism OMIM:[147670], Rabson-Mendenhall syndrome OMIM:[147670]

About this StructureAbout this Structure

2AUH is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

ReferenceReference

[xtra 1]

  1. Depetris RS, Hu J, Gimpelevich I, Holt LJ, Daly RJ, Hubbard SR. Structural basis for inhibition of the insulin receptor by the adaptor protein Grb14. Mol Cell. 2005 Oct 28;20(2):325-33. PMID:16246733 doi:10.1016/j.molcel.2005.09.001

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