2pwr

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Template:STRUCTURE 2pwr

File:2pwr.png

HIV-1 protease in complex with a carbamoyl decorated pyrrolidine-based inhibitorHIV-1 protease in complex with a carbamoyl decorated pyrrolidine-based inhibitor

Template:ABSTRACT PUBMED 18348517

About this StructureAbout this Structure

2PWR is a 2 chains structure of sequences from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.

ReferenceReference

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↑ Blum A, Bottcher J, Heine A, Klebe G, Diederich WE. Structure-Guided Design of C2-Symmetric HIV-1 Protease Inhibitors Based on a Pyrrolidine Scaffold. J Med Chem. 2008 Apr 10;51(7):2078-87. Epub 2008 Mar 19. PMID:18348517 doi:10.1021/jm701142s

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OCA

[1] Blum A, Bottcher J, Heine A, Klebe G, Diederich WE. Structure-Guided Design of C2-Symmetric HIV-1 Protease Inhibitors Based on a Pyrrolidine Scaffold. J Med Chem. 2008 Apr 10;51(7):2078-87. Epub 2008 Mar 19. PMID:18348517 doi:10.1021/jm701142s

[xtra 1]