1kw0
Catalytic Domain of Human Phenylalanine Hydroxylase (Fe(II)) in Complex with Tetrahydrobiopterin and ThienylalanineCatalytic Domain of Human Phenylalanine Hydroxylase (Fe(II)) in Complex with Tetrahydrobiopterin and Thienylalanine
Template:ABSTRACT PUBMED 12126628
DiseaseDisease
Known disease associated with this structure: Phenylketonuria OMIM:[612349], Hyperphenylalaninemia, mild OMIM:[612349]
About this StructureAbout this Structure
1KW0 is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
ReferenceReference
- ↑ Andersen OA, Flatmark T, Hough E. Crystal structure of the ternary complex of the catalytic domain of human phenylalanine hydroxylase with tetrahydrobiopterin and 3-(2-thienyl)-L-alanine, and its implications for the mechanism of catalysis and substrate activation. J Mol Biol. 2002 Jul 26;320(5):1095-108. PMID:12126628
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