1o0d

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File:1o0d.png

Template:STRUCTURE 1o0d

Human Thrombin complexed with a d-Phe-Pro-Arg-type Inhibitor and a C-terminal Hirudin derived exo-site inhibitorHuman Thrombin complexed with a d-Phe-Pro-Arg-type Inhibitor and a C-terminal Hirudin derived exo-site inhibitor

Template:ABSTRACT PUBMED 12781189

DiseaseDisease

Known disease associated with this structure: Dysprothrombinemia OMIM:[176930], Hyperprothrombinemia OMIM:[176930], Hypoprothrombinemia OMIM:[176930]

About this StructureAbout this Structure

1O0D is a 3 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

ReferenceReference

[xtra 1]

  1. Lange UE, Baucke D, Hornberger W, Mack H, Seitz W, Hoffken HW. D-Phe-Pro-Arg type thrombin inhibitors: unexpected selectivity by modification of the P1 moiety. Bioorg Med Chem Lett. 2003 Jun 16;13(12):2029-33. PMID:12781189

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