2ds1

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Template:STRUCTURE 2ds1

File:2ds1.png

Human cyclin dependent kinase 2 complexed with the CDK4 inhibitorHuman cyclin dependent kinase 2 complexed with the CDK4 inhibitor

Template:ABSTRACT PUBMED 16876403

About this StructureAbout this Structure

2DS1 is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

ReferenceReference

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↑ Kawanishi N, Sugimoto T, Shibata J, Nakamura K, Masutani K, Ikuta M, Hirai H. Structure-based drug design of a highly potent CDK1,2,4,6 inhibitor with novel macrocyclic quinoxalin-2-one structure. Bioorg Med Chem Lett. 2006 Oct 1;16(19):5122-6. Epub 2006 Jul 28. PMID:16876403 doi:10.1016/j.bmcl.2006.07.026

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OCA

[1] Kawanishi N, Sugimoto T, Shibata J, Nakamura K, Masutani K, Ikuta M, Hirai H. Structure-based drug design of a highly potent CDK1,2,4,6 inhibitor with novel macrocyclic quinoxalin-2-one structure. Bioorg Med Chem Lett. 2006 Oct 1;16(19):5122-6. Epub 2006 Jul 28. PMID:16876403 doi:10.1016/j.bmcl.2006.07.026

[xtra 1]