2hu6

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Template:STRUCTURE 2hu6

File:2hu6.png

Crystal structure of human MMP-12 in complex with acetohydroxamic acid and a bicyclic inhibitorCrystal structure of human MMP-12 in complex with acetohydroxamic acid and a bicyclic inhibitor

Template:ABSTRACT PUBMED 16899369

About this StructureAbout this Structure

2HU6 is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

ReferenceReference

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↑ Mannino C, Nievo M, Machetti F, Papakyriakou A, Calderone V, Fragai M, Guarna A. Synthesis of bicyclic molecular scaffolds (BTAa): an investigation towards new selective MMP-12 inhibitors. Bioorg Med Chem. 2006 Nov 15;14(22):7392-403. Epub 2006 Aug 8. PMID:16899369 doi:10.1016/j.bmc.2006.07.028

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OCA

[1] Mannino C, Nievo M, Machetti F, Papakyriakou A, Calderone V, Fragai M, Guarna A. Synthesis of bicyclic molecular scaffolds (BTAa): an investigation towards new selective MMP-12 inhibitors. Bioorg Med Chem. 2006 Nov 15;14(22):7392-403. Epub 2006 Aug 8. PMID:16899369 doi:10.1016/j.bmc.2006.07.028

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