2pl0
LCK bound to imatinibLCK bound to imatinib
Template:ABSTRACT PUBMED 17910071
DiseaseDisease
Known disease associated with this structure: SCID due to LCK deficiency OMIM:[153390]
About this StructureAbout this Structure
2PL0 is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
ReferenceReference
- ↑ Jacobs MD, Caron PR, Hare BJ. Classifying protein kinase structures guides use of ligand-selectivity profiles to predict inactive conformations: Structure of lck/imatinib complex. Proteins. 2007 Oct 1;70(4):1451-1460. PMID:17910071 doi:10.1002/prot.21633
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