2gnf

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File:2gnf.png

Template:STRUCTURE 2gnf

Protein kinase A fivefold mutant model of Rho-kinase with Y-27632Protein kinase A fivefold mutant model of Rho-kinase with Y-27632

Template:ABSTRACT PUBMED 16699172

About this StructureAbout this Structure

2GNF is a 2 chains structure of sequences from Bos taurus. Full crystallographic information is available from OCA.

ReferenceReference

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↑ Bonn S, Herrero S, Breitenlechner CB, Erlbruch A, Lehmann W, Engh RA, Gassel M, Bossemeyer D. Structural analysis of protein kinase A mutants with Rho-kinase inhibitor specificity. J Biol Chem. 2006 Aug 25;281(34):24818-30. Epub 2006 May 12. PMID:16699172 doi:10.1074/jbc.M512374200
↑ Breitenlechner C, Gassel M, Hidaka H, Kinzel V, Huber R, Engh RA, Bossemeyer D. Protein kinase A in complex with Rho-kinase inhibitors Y-27632, Fasudil, and H-1152P: structural basis of selectivity. Structure. 2003 Dec;11(12):1595-607. PMID:14656443

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OCA

[1] Bonn S, Herrero S, Breitenlechner CB, Erlbruch A, Lehmann W, Engh RA, Gassel M, Bossemeyer D. Structural analysis of protein kinase A mutants with Rho-kinase inhibitor specificity. J Biol Chem. 2006 Aug 25;281(34):24818-30. Epub 2006 May 12. PMID:16699172 doi:10.1074/jbc.M512374200

[2] Breitenlechner C, Gassel M, Hidaka H, Kinzel V, Huber R, Engh RA, Bossemeyer D. Protein kinase A in complex with Rho-kinase inhibitors Y-27632, Fasudil, and H-1152P: structural basis of selectivity. Structure. 2003 Dec;11(12):1595-607. PMID:14656443

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