2i1r

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File:2i1r.png

Template:STRUCTURE 2i1r

Novel Thiazolones as HCV NS5B Polymerase Inhibitors: Further Designs, Synthesis, SAR and X-ray Complex StructureNovel Thiazolones as HCV NS5B Polymerase Inhibitors: Further Designs, Synthesis, SAR and X-ray Complex Structure

Template:ABSTRACT PUBMED 17049849

About this StructureAbout this Structure

2I1R is a 2 chains structure of sequences from Hepatitis c virus. Full crystallographic information is available from OCA.

ReferenceReference

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↑ Yan S, Larson G, Wu JZ, Appleby T, Ding Y, Hamatake R, Hong Z, Yao N. Novel thiazolones as HCV NS5B polymerase allosteric inhibitors: Further designs, SAR, and X-ray complex structure. Bioorg Med Chem Lett. 2007 Jan 1;17(1):63-7. Epub 2006 Oct 4. PMID:17049849 doi:10.1016/j.bmcl.2006.09.095

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OCA

[1] Yan S, Larson G, Wu JZ, Appleby T, Ding Y, Hamatake R, Hong Z, Yao N. Novel thiazolones as HCV NS5B polymerase allosteric inhibitors: Further designs, SAR, and X-ray complex structure. Bioorg Med Chem Lett. 2007 Jan 1;17(1):63-7. Epub 2006 Oct 4. PMID:17049849 doi:10.1016/j.bmcl.2006.09.095

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