3dxe
Crystal structure of the intracellular domain of human APP (T668A mutant) in complex with Fe65-PTB2Crystal structure of the intracellular domain of human APP (T668A mutant) in complex with Fe65-PTB2
Template:ABSTRACT PUBMED 18833287
About this StructureAbout this Structure
3DXE is a 4 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.
ReferenceReference
- ↑ Radzimanowski J, Simon B, Sattler M, Beyreuther K, Sinning I, Wild K. Structure of the intracellular domain of the amyloid precursor protein in complex with Fe65-PTB2. EMBO Rep. 2008 Nov;9(11):1134-40. Epub 2008 Oct 3. PMID:18833287 doi:http://dx.doi.org/10.1038/embor.2008.188
- ↑ Radzimanowski J, Beyreuther K, Sinning I, Wild K. Overproduction, purification, crystallization and preliminary X-ray analysis of human Fe65-PTB2 in complex with the amyloid precursor protein intracellular domain. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2008 May 1;64(Pt, 5):409-12. Epub 2008 Apr 24. PMID:18453713 doi:http://dx.doi.org/10.1107/S1744309108009524
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OCACategories:
- Pages with broken file links
- Homo sapiens
- Radzimanowski, J.
- Sinning, I.
- Wild, K.
- Aicd
- Alternative splicing
- Alzheimer disease
- Alzheimer's disease
- Amyloid
- Apoptosis
- App
- Cell adhesion
- Coated pit
- Copper
- Disease mutation
- Endocytosis
- Fe65
- Glycoprotein
- Heparin-binding
- Iron
- Membrane
- Metal-binding
- Notch signaling pathway
- Phosphoprotein
- Polymorphism
- Protease inhibitor
- Protein binding
- Proteoglycan
- Ptb domain
- Serine protease inhibitor
- Transmembrane
- Zinc