3faa
Crystal structure of TGFbRI complexed with a 2-aminoimidazole inhibitorCrystal structure of TGFbRI complexed with a 2-aminoimidazole inhibitor
Template:ABSTRACT PUBMED 19135364
DiseaseDisease
Known disease associated with this structure: Loeys-Dietz syndrome, type 1A OMIM:[190181], Loeys-Dietz syndrome, type 2A OMIM:[190181]
About this StructureAbout this Structure
3FAA is a 5 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.
ReferenceReference
- ↑ Bonafoux D, Chuaqui C, Boriack-Sjodin PA, Fitch C, Hankins G, Josiah S, Black C, Hetu G, Ling L, Lee WC. 2-Aminoimidazoles inhibitors of TGF-beta receptor 1. Bioorg Med Chem Lett. 2009 Feb 1;19(3):912-6. Epub 2008 Dec 11. PMID:19135364 doi:10.1016/j.bmcl.2008.11.119
Page seeded by OCA on Sun Feb 15 08:48:13 2009
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OCACategories:
- Pages with broken file links
- Homo sapiens
- Receptor protein serine/threonine kinase
- Boriack-Sjodin, P A.
- Fitch, C.
- Atp-binding
- Craniosynostosis
- Disease mutation
- Glycoprotein
- Kinase
- Magnesium
- Manganese
- Membrane
- Metal-binding
- Nucleotide-binding
- Phosphoprotein
- Polymorphism
- Protein-inhibitor complex
- Receptor
- Serine/threonine-protein kinase
- Structure-based drug design
- Tgfbeta
- Transferase
- Transmembrane