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Classification and catalytic centerClassification and catalytic center
Thermolysin is a well researched metallo protease containing and several calcium atoms (yellow). The catalytic center consists of the HEXHH motif.
, holding it fast, while stabilize the substrate.[1][2]
On the Routine Use of Soft X-Rays in Macromolecular Crystallography, Part III- The Optimal Data Collection WavelengthOn the Routine Use of Soft X-Rays in Macromolecular Crystallography, Part III- The Optimal Data Collection Wavelength
↑Matthews, BW. (1988): Structural basis of the action of thermolysin and related zinc peptidases. In: Acc. Chem. Res.21(9); 333–340; http://dx.doi.org/10.1021/ar00153a003
↑Pelmenschikov V, Blomberg MR, Siegbahn PE. A theoretical study of the mechanism for peptide hydrolysis by thermolysin. J Biol Inorg Chem. 2002 Mar;7(3):284-98. Epub 2001 Sep 27. PMID:11935352 doi:http://dx.doi.org/10.1007/s007750100295
