1wae
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CRYSTAL STRUCTURE OF H129V MUTANT OF ALCALIGENES XYLOSOXIDANS NITRITE REDUCTASE
OverviewOverview
Copper nitrite reductases contain both an electron-transfer type 1 Cu site, and a catalytic type 2 Cu site. We have mutated one of the type 2 copper, ligating histidines to observe the effect on catalytic turnover. This, mutation has created a unique site where Cu is ligated by 2 His Nepsilon2, atoms alone.
About this StructureAbout this Structure
1WAE is a [Single protein] structure of sequence from [Alcaligenes xylosoxydans xylosoxydans] with CU and ZN as [ligands]. Active as [[1]], with EC number [1.7.99.3]. Full crystallographic information is available from [OCA].
ReferenceReference
Observation of an unprecedented Cu Bis-His site: crystal structure of the H129V mutant of nitrite reductase., Ellis MJ, Antonyuk SV, Strange RW, Sawers G, Eady RR, Hasnain SS, Inorg Chem. 2004 Nov 29;43(24):7591-3. PMID:15554622
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